Snap-8 peptide, or Acetyl Octapeptide-3, is an elongation of the famous hexapeptide, Argireline. This biomimetic peptide is renowned for its anti-wrinkle properties and is increasingly being utilized in the realm of cosmeceuticals.
The mechanism of action of Snap-8 involves modulating muscle contraction. Specifically, it targets the SNARE complex, a set of proteins that mediates vesicle trafficking and neurotransmitter release. Research has shown by impeding the formation of this complex, Snap-8 reduces the release of acetylcholine, a neurotransmitter involved in muscle contraction. The resulting effect is a reduction in the intensity of facial muscle contractions, leading to a decrease in the appearance of expression lines and wrinkles.
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[1] https://www.frontiersin.org/articles/ 10.3389/fchem.2020.572923/full
[2] https://www.sciencedirect.com/ science/article/pii/S096808961731653X
[3] https://onlinelibrary.wiley.com/ doi/abs/10.1111/jocd.13009
[4] https://www.mdpi.com/2079-9284/7/4/91
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