Buy Selank Peptide Netherlands
Buy Selank, a synthetic peptide with anxiolytic properties, known for its potential benefits in reducing anxiety, enhancing cognitive function, and supporting immune system regulation, particularly in research and laboratory settings.
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NEWSemax Selank Peptide Stack
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Selank Peptide Vial
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Selank Pre-Mixed Pen 5mg Peptide
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Selank Nasal Spray
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Selank Semax Nasal Stack
Price range: £68.87 through £126.95 This product has multiple variants. The options may be chosen on the product page
What Is Selank Peptide?
Selank is a synthetic heptapeptide, consisting of 7 amino acids. It belongs to the class of nootropic and anxiolytic compounds designed specifically for research purposes. Structurally, it is derived from the endogenous peptide tuftsin, which plays a role in immune system regulation.
It has gained significant attention for its potential effects on reducing anxiety, improving cognitive performance, and modulating the immune response. Unlike traditional benzodiazepines, it is believed to exert its effects via mechanisms that involve modulation of neurotransmitters like serotonin and dopamine, as well as influencing the expression of brain-derived neurotrophic factors (BDNF).
This peptide is primarily explored in the context of investigating its potential therapeutic applications for anxiety disorders, stress-related conditions, and cognitive impairments. Additionally, pre-clinical and laboratory studies often aim to better understand its interaction with the central nervous system and its potential neuroprotective benefits.
Owing to its unique properties, it presents a promising avenue for advancing knowledge in neuropharmacology and immune research, provided it is used strictly under controlled, professional, and non-human experimental conditions.
Selank Mechanism Of Action
It’s mechanism of action is multifaceted, involving both direct and indirect pathways within the central nervous system. It is known to influence the regulation of key neurotransmitters, particularly serotonin and dopamine, which are critical in maintaining mood stability, emotional balance, and cognitive function.
By modulating these neurotransmitters, it may help alleviate symptoms of anxiety, enhance focus, and improve overall mental clarity. Additionally, research suggests that it stimulates the expression of brain-derived neurotrophic factor (BDNF), a protein that plays a vital role in neurogenesis, synaptic plasticity, and overall brain health.
Furthermore, it has demonstrated immunomodulatory effects, particularly in modulating the expression of cytokines—protein molecules involved in immune system signalling. This dual action on both neurological and immunological pathways highlights its potential as a peptide with wide-ranging therapeutic applications. While the exact biochemical processes continue to be studied, it’s impact on neuropeptide regulation reinforces its role as a novel agent of interest in the fields of neuroscience and immunology.
Structure of Selank Peptide
Sequence: H-Thr-Lys-Pro-Arg-Pro-Gly-Pro-OH
Molecular Formula: C33H57N11O9
Molecular Weight: 751.9 g/mol
PubChem CID: 11765600
What Are The Research Benefits of Selank?
Effects on Gene Expression: Studies suggest that it can influence the behaviour of certain genes in the brain, particularly those involved in GABAergic neurotransmission. This system relies on GABA receptors to regulate mood, relaxation, and stress responses. By interacting with these genes, it may help to adjust the balance of this neurochemical system. Its effects could mirror those of GABA receptor agonists, such as diazepam, potentially leading to calming and anxiolytic effects. This indicates that it might play an important role in supporting the brain’s natural mechanisms for managing stress and enhancing mental well-being [1].
Anxiolytic Effects: It has been shown to reduce symptoms of anxiety by modulating neurotransmitter levels such as serotonin and dopamine, which are essential for emotional regulation and mood stability. Generalized anxiety is linked to reduced enkephalinase activity and shorter enkephalin half-life due to low enzyme inhibitors [2]. One study showed the heptapeptide effectively inhibits enkephalin breakdown, outperforming other inhibitors, which may explain its potential in treating anxiety and phobic disorders [3].
Potential Anti-inflammatory Properties: By modulating immune system responses, it may contribute to reducing inflammation, benefiting individuals with immune-related disorders. One study examined the effects on inflammation-related gene expression in mouse spleens. Using real-time PCR, researchers analyzed 84 inflammation-associated genes 6 and 24 hours after Selank injection. Significant changes were observed in 34 genes, including Bcl6, a key regulator of immune system development. Findings suggest that Selank influences inflammation processes by altering genomic expression, highlighting its potential role in immune regulation [4].
Memory Improvement: Research suggests it may help enhance memory formation and retention due to its role in modulating chemical pathways related to learning. Netherlands Researchers studied the effects of selank on learning, memory, and attention in Wistar rats treated with a neurotoxin damaging catecholaminergic neurons. Selank (300 µg/kg) successfully restored cognitive functions impaired by the disrupted catecholaminergic system [5].
Stress Resilience: It helps stabilize neurotransmitter levels, supporting the body’s natural ability to stay calm and resilient under stress. In a study on rats, the peptide was more effective than diazepam at reducing anxiety caused by test substances under normal conditions. Under chronic stress, combining Selank with diazepam worked best, but the peptide caused fewer negative anxiety-related side effects compared to diazepam [6].
Immunomodulation: It influences cytokine expression, helping to regulate immune system activity and potentially mitigating inflammation-related conditions [7].
Alcohol Withdrawal: A study on rats showed that a single dose of selank (0.3 mg/kg) effectively reduced anxiety and mechanical allodynia caused by 48-hour alcohol withdrawal, without altering ethanol consumption. These results suggest it may help alleviate alcohol withdrawal symptoms [8].
Buy Selank Netherlands for laboratory research use online today!
Buy Selank Pre-Mixed Pen
Buy Selank pre-mixed pen, a convenient, accurate, and easy-to-use solution for peptide administration. With adjustable dosing and fine needle tips, they simplify treatment, save time, and enhance adherence to therapy protocols.
Pre-Mixed Cartridge Kits include a cartridge (premixed with your chosen peptide and bacteriostatic water), a pen, case, and needle tips. Single Cartridges (1, 2, or 3) include cartridges and needle tips but no kit. Save 10% on a 3-cartridge purchase!
Buy Selank Semax Nasal Stack
Buy Selank and Semax Nasal Spray Stack, it combines two powerful peptides—Selank for anxiety relief and emotional balance, and Semax for cognitive enhancement and stress resilience.
Available in 15ml or 30ml options, this convenient nasal spray stack offers an easy, non-invasive solution for research on mental clarity.
There is also the option to buy Selank and Semax vial stack.
Frequently Asked Questions (FAQs) about Selank
Is Selank safe to use?
Studies suggest that it is generally well-tolerated and does not produce significant side effects. However, the compound, its safety and efficacy may vary between individuals, and further research is ongoing.
How is Selank administered?
It is typically administered as a nasal spray, which allows for rapid absorption. This delivery method is non-invasive and convenient for users.
Can Selank be combined with other medications?
Research indicates that it can be combined with certain medications, such as diazepam, to enhance its effectiveness under specific conditions, such as chronic stress. However, combinations should only be taken under professional medical guidance.
Is Selank legal?
The legal status varies depending on the country. While it is approved for medical use in some countries, such as Russia, use of this product has not been approved by the U.S. Food and Drug Administration (FDA) for human consumption of any kind.
This means it is not legally available as a prescription medication in the United States. However, it may be obtained in some regions as a research compound. It is essential to be aware of and comply with local regulations regarding its purchase and use.
Is Selank addictive?
Unlike some traditional anti-anxiety medications, Selank has not shown addictive properties in studies, making it a potentially safer option for long-term use.
Buy Selank Netherlands for in vitro and in vivo laboratory research use from Direct Peptides.
Summary of Research Applications
- Potential treatment of anxiety disorders.
- Helps reduce stress.
- Improves memory and learning.
- Boosts immunity.
- Anti-inflammatory properties.
- Helps reduce brain fog.
Selank Peptide Quality Assured
Buy Selank peptide with 99% purity from Direct Peptides, designed to support your scientific research on anxiety and cognitive function. Explore our website to learn more about our products, shipping policies, purity certificates, and research uses.
We third-party test our products to ensure quality and reliability, so you can trust your results. We focus on safety, precision, and consistency to provide everything your research needs to succeed.
References For Further Reading
[1] Anastasiya Volkova, Maria Shadrina, Timur Kolomin, Lyudmila Andreeva, et al (2016) Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission – Frontiers in Pharmacology, 2016 Feb 18, Volume 7, Page 31.
[2] T. Syunyakov, E.S. Teleshova, G.G. Neznamov, and V.K. Bochkarev (2012) P-1114 – Rapid and slow response during treatment of generalized anxiety disorder with peptide anxiolytic selank – European Psychiatry, Volume 27, Supplement 1, 2012, Page 1.
[3] A A Zozulya, N V Kost, O Yu Sokolov, M V Gabaeva, I A Grivennikov, et al (2001) The inhibitory effect of Selank on enkephalin-degrading enzymes as a possible mechanism of its anxiolytic activity – Bulletin of Experimental Biology and Medicine, 2001 Apr, Volume 131 (Issue 4), Pages 315-7.
[4] Timur Kolomin, Maria Shadrina, Lyudmila Andreeva, Petr Slominsky, et al (2011) Expression of inflammation-related genes in mouse spleen under tuftsin analog Selank – Regulatory Peptides, 2011 Oct 10, Volume 170 (Issue 1-3), Pages 18-23.
[5] T P Semenova, M M Kozlovskaya, N M Zakharova, I I Kozlovskii, A V Zuikov (2007) Effect of selank on cognitive processes after damage inflicted to the cerebral catecholamine system during early ontogeny – Bulletin of Experimental Biology & Medicine, 2007 Nov, Volume 144 (Issue 5), Pages 689-91.
[6] Anastasiya Kasian, Timur Kolomin, Lyudmila Andreeva, Elena Bondarenko, et al (2017) Peptide Selank Enhances the Effect of Diazepam in Reducing Anxiety in Unpredictable Chronic Mild Stress Conditions in Rats – Behavioural Neurology, 2017 Feb 9, Volume 2017, Page 5091027.
[7] Yasenyavskaya A Leonidovna, Samotrueva M Aleksandrovna, Tsibizova A Aleksandrovna, et al (2021) The Influence of Selank on the Level of Cytokines Under the Conditions of “Social” Stress – Current Reviews in Clinical and Experminetal Pharmacology, 2021, Volume 16 (Issue 2), Pages 162-167.
[8] L G Kolik, A V Nadorova, and M M Kozlovskaya (2014) Efficacy of peptide anxiolytic selank during modeling of withdrawal syndrome in rats with stable alcoholic motivation – Bulletin of Experimental Biology and Medicine, 2014 May, Volume 157 (Issue 1), Pages 52-5.
Why Choose Direct Peptides Netherlands?
Buy Selank Netherlands from Direct Peptides, your trusted source for premium peptides. What sets us apart is our diverse range of innovative formulations, including 5 mg peptide vials, peptide stacks designed for potential synergistic benefits, convenient nasal sprays available in 15ml and 30ml bottles, and pre-mixed peptide pens.
ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.
DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Netherlands Direct Peptides website: https://netherlands.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.
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